Fly-half Finn Russell has been passed fit to start, but winger Darcy Graham has not fully recovered from their first-half collision against Ireland that saw both players suffer concussions. Graham has been replaced by Glasgow Warriors’ Kyle Rowe.
In the pack, loose-head prop Pierre Schoeman and flanker Jamie Ritchie come into the starting XV with Rory Sutherland and Matt Fagerson dropping to the bench.
Scotland: 15-Kinghorn; 14-Rowe, 13-Jones, 12-Jordan, 11-Van der Merwe; 10- Russell (co-capt), 9-White; 1-Schoeman, 2-Cherry, 3-Z. Fagerson, 4-Gray; 5-Gilchrist, 6-Ritchie, 7-Darge (co-capt), 8-Dempsey
Replacements: 16-Ashman, 17-Sutherland, 18-Hurd, 19-Skinner, 20-Brown, 21-M. Fagerson, 22-Dobie, 23-McDowall