Ireland say that Tadhg Furlong, Mack Hansen and Joe McCarthy “continue to make good progress” in their returns from injury.
Forwards Furlong and McCarthy have not featured in the 2025 Six Nations, missing the wins over England and Scotland with calf and head injuries respectively.
Wing Hansen started against England, and was originally named to play against Scotland, but was replaced by Calvin Nash for the 32-18 win in Murrayfield.
Ireland are top of the Six Nations table with a maximum 10 points from their two games and are next in action against Wales on 22 February.
An Irish Rugby Football Union [IRFU] statement said the side are “optimistic” the trio will be involved in the Principality Stadium.
Ireland reported no fresh injury concerns after their win in Edinburgh with some of those not involved set to be released to their provinces for United Rugby Championship [URC] action this weekend.